Thursday, July 14, 2011

What directs linear DNA to form chromosomes with perfect X shapes with a centromere?

Is there a certain molecule involved that comes out and starts pushing the supercoiled DNA into the X shaped chromosome? I know histones are involved but every single damn time the thing becomes an X or a partial X with a centromere. How does it happen? How the hell does it know to do that so that the spindle fibers can later move it to the sides?

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